It might not work and you might be asking for trouble or a massive headache to attempt something like this Hook LOL, every rewire application I ever used such as reason, Fruity -dxi-vst not rewire oops and ableton have to be locally run, the host rewire and the rewire client app, because the way the api's for those programs are written they search locally for the rewire application to launch on the active channel, I do not think this is possible or actually even a good idea because of the overhead that would be introduced, how would you make the them synchronize though?....midi?? it's enuff trouble to get my rewire apps to run locally all the time, the only time I use rewire with reason is to use my VST's from Waves with reason or from Ableton..........again I could be wrong but I don't think this is possible right now.